GRANTS
- GRANTA Phase 2/3, Randomized Study of INBRX-106 Combined With Pembrolizumab Versus Pembrolizumab as First Line Treatment for Patients With Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) Expressing PD-L1 (CPS = 20) (HexAgon-HN)Inhibrx Biosciences23 Sep 2025 - 22 Sep 2030
- GRANTPragmatica-Lung: A PROSPECTIVE RANDOMIZED STUDY OF RAMUCIRUMAB (LY3009806; NSC 749128) PLUS PEMBROLIZUMAB (MK-3475; NSC 776864) VERSUS STANDARD OF CARE FOR PARTICIPANTS PREVIOUSLY TREATED WITH IMMUNOTHERAPY FOR STAGE IV OR RECURRENT NON-SMALL CELL LUNG CANational Institute of Health Nci6 Mar 2023 - 28 Feb 2026
- GRANTA Phase 2, randomized, open-label three-arm clinical study to evaluate the safety and efficacy of lenvatinib (E7080/MK-7902) in combination with pembrolizumab (MK-3475) versus standard of care chemotherapy and lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) that have progressed after platinum therapy and immunotherapy (PD-1/PD-L1 inhibitors) (LEAP-009)Merck Sharp & Dohme26 Oct 2020 - 26 Jan 2025
- GRANTA Phase 2, randomized, open-label three-arm clinical study to evaluate the safety and efficacy of lenvatinib (E7080/MK-7902) in combination with pembrolizumab (MK-3475) versus standard of care chemotherapy and lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) that have progressed after platinum therapy and immunotherapy (PD-1/PD-L1 inhibitors) (LEAP-009)#Merck Sharp & Dohme26 Oct 2020 - 25 Oct 2025
- GRANTAn Open-label, Multi-center, Phase 1b/2 Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid TumorsBayer Healthcare Pharmaceuticals19 Dec 2019 - 10 Aug 2021
- GRANTSMARTPLUS-106: Debio 1143 a SMAC Mimetic in Combination with Nivolumab in Patients Failing Prior PD-1/PD-L1 Treatment: A Basket TrialDebiopharm Sa19 Nov 2019 - 16 Dec 2022
- GRANTLIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMABNational Institute of Health Nci22 Jul 2019 - 28 Feb 2029
- GRANTLIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMABGenentech Inc22 Jul 2019 - 31 Dec 2024
- GRANTLIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMAB#Genentech Inc22 Jul 2019 - 20 Aug 2026
- GRANTEA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNaNational Institute of Health Nci28 Feb 2019 - 28 Feb 2026
- GRANTRandomized Phase II Clinical Trial of Cisplatin/Carboplatin and Etoposide (CE) Alone or in Combination With Nivolumab as Frontline Therapy for Extensive Stage Small Cell Lung Cancer (ED-SCLC)National Institute of Health Nci2 Jul 2018 - 1 Jul 2023
- GRANTA Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Subjects with Extensive Stage Small Cell Lung Cancer (MERU)Abbvie5 Oct 2017 - 18 Mar 2020
- GRANTA Phase II Trial of TAS-102 in Previously Treated Unresectable or Metastatic Squamous Cell Carcinoma of the LungTaiho Oncology Inc7 Jun 2017 - 19 Jan 2023
- GRANTA Non-Randomized Phase Ib-II Protocol of Paclitaxel, Carboplatin and the Dual P13K/mTOR Kinase Inhibitor, PF-05212384 (Gedatolisib), in Patients with Advanced or Metastatic Non-Small Cell Carcinoma of the LungPfizer Inc15 Nov 2016 - 30 Oct 2021
- GRANTA RANDOMIZED, OPEN-LABEL, MULTI-CENTER, INTERNATIONAL PHASE 2 STUDY OF TAS-114 IN COMBINATION WITH S-1 IN PATIENTS WITH ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCERTaiho Oncology Inc19 Oct 2016 - 18 Oct 2021
- GRANTA Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 In Completely Resected Non-Small Cell Lung Cancer*clinipace Inc7 May 2015 - 5 Jul 2023